孕妇血清血型抗体滴度对ABO新生儿溶血病的影响
张添新 1原敏 1甘玮玮1
作者信息
- 1. 福建医科大学附属漳州市医院 363000
- 折叠
摘要
目的：检测孕妇产前血清血型抗体IgG抗A抗B滴度，分析其对ABO新生儿溶血病的影响。方法：采用微柱凝胶法对1476例O型孕妇（其丈夫血型为A、B或AB型）在32周左右检测血型抗体滴度，高胆红素血症患儿做溶血三项试验。结果：1476例O型孕妇血清中IgG抗A抗B滴度<1：64组为645例，1：64-1：128组为601例，>1：128组为230例，各组新生儿溶血病发病例数为<1：64组为2例，1：64-1：128组为83例，>1：128组为56例，各组发病率差异有统计学意义（P<0.05）。结论：孕妇产前检测血清血型抗体滴度对ABO新生儿溶血病的预防和治疗有着积极意义。
Abstract
Objective To detect the serum IgG of pregnant women blood group antibodies of anti A and anti B titer, analyzes its in-fluence on ABO hemolytic disease of newborn. Methods Microcolumn gel technique in 1476 cases of O in pregnant women (whose husband blood type is A, B or AB) at around 32 weeks of testing the titer of blood group antibody, hyperbilirubinemia do hemolytic three test. Results 1476 cases of type O in maternal serum IgG anti A and anti B titer of<1:64 group was 645 cases, 601 cases in group 1:64-1:128, 230 cases in group>1:128, each group of hemolytic disease of the newborn cases number of<1:64 group was 2 cases, 83 cases in group 1:64-1:128, 56 cases in group>1:128, the difference was statistically significant in each group incidence (P<0.05).Con-clusion It has positive significance for prevention and treatment of conclusion prenatal detection of serum antibody titers of blood group ABO hemolytic disease of newborn.
关键词
血型抗体滴度/ABO新生儿溶血病/微柱凝胶法Key words
the titer of blood group antibody/ABO hemolytic disease of the newborn/microcolumn gel technique引用本文复制引用
出版年
2015
NETL
NSTL
万方数据