Objective: To investigate the safety evaluation and risk management assessment of pantoprazole in clinical applications, improve the clinical level third generation proton pump inhibitor drugs. Methods:A retrospective study of large- scale clinical inclusion in our hospital from January 2013 to November 2014 using the patient pantoprazole and omeprazole, the incidence of adverse drug re-actions observed in the incidence and adverse symptoms;elderly patients adverse reactions and adverse reactions critical of occurrence;to overdose and adverse long- term treatment were analyzed initially established treatment options for risk management. Results:The inci-dence of adverse reactions with pantoprazole, the incidence of adverse symptoms of less than omeprazole;incidence in elderly patients is not higher than in younger patients, the incidence of severe adverse reactions is not high;excessive and long- term treatment adverse re-actions are not increased;hospitals to establish specialized risk management system can effectively reduce the risk of medication. Conclu-sion:pantoprazole can safely and efficiently inhibit gastric acid secretion fast, clinical sound risk management system can be effective and rational use of drugs.
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