Objective:To study the clinical features of poisoning patients in emergency intensive care unit, and carries on the analy-sis. Methods:study 52 poisoning patients on ICU in our hospital were retrospectively analyzed the situation, rescue, the poisoning clini-cal data and epidemiological characteristics. Results: all the poisoning patients, female poisoning ratio of 61.5% is considered the male 38.5%high, compare the two X- =5.4852 (p=0.0192), with significant difference. According to the poisoning patients adopt different methods of treatment, in addition to death with the rescue invalid 1 cases of paraquat poisoning, the rest were improved and discharged. Conclusion:the clinical characteristics of the patients in ICU of poisoning were analyzed, conducive to understanding the mechanism of poisoning, and provides an effective guarantee for the clinical treatment of.