首页|麝香保心丸联合曲美他嗪治疗老年缺血性心肌病心力衰竭患者的临床疗效探讨

麝香保心丸联合曲美他嗪治疗老年缺血性心肌病心力衰竭患者的临床疗效探讨

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目的::讨论麝香保心丸与曲美他嗪联用治疗老年缺血性心肌病心力衰竭的效果。方法:回顾性分析重庆医科大学附属第一医院2011年3月至2013年12月期间收治的54例老年缺血性心肌病心力衰竭病人的临床资料,根据病人的入院尾号分为对照组(单用曲美他嗪)与研究组(麝香保心丸与曲美他嗪联用),每组各27例。对比两组病人的临床疗效、左室射血分数、左室收缩末内径、左室舒张末内径指标、6分钟步行试验评价以及不良反应几率。结果:通过半年的治疗以后,研究组病人的6分钟步行试验评价、左室舒张末内径指标、左室收缩末内径、左室射血分数以及临床总有效率都要显著优于对照组病人,差异具有统计学意义(P<0.05);对照组与研究组的不良反应发生率对比不具有统计学意义(P>0.05)。结论:针对老年缺血性心肌病心力衰竭病人,采用麝香保心丸联合曲美他嗪进行治疗具有临床疗效好、安全性高的优势,对提升病人的生活质量具有十分重要的现实意义。
Objective:HMP discussion with the effect of trimetazidine treatment of elderly patients with ischemic cardiomyopathy and heart failure associated with. Methods: A retrospective analysis of the First Affiliated Hospital of Chongqing Medical University, treated from March 2011 to December 2013 during the clinical data of 54 cases of elderly patients with ischemic cardiomyopathy and heart failure, according to the patient's admission into the tail number of the control group (alone trimetazidine) and Research group (HMP with trimetazidine combined with), 27 cases in each group. Clinical comparative study of two groups of patients, left ventricular ejection fraction, left ventricular end- systolic diameter, left ventricular end- diastolic diameter index, 6- minute walk test and evaluation of the probability of adverse reactions. The result:By six months after treatment, the 6- minute walk test evaluation study group of pa-tients with left ventricular end- diastolic diameter index, left ventricular end- systolic diameter, left ventricular ejection fraction and clin-ical total effective rate should be significantly better than patients in the control group, the difference statistically significant (P<0.05);incidence of adverse reactions in the control group and the study group was not statistically significant comparison (P>0.05). Conclu-sion:For elderly heart failure patients with ischemic cardiomyopathy, using HMP joint trimetazidine treatment with good clinical effica-cy, high security advantages, to enhance the quality of life of patients with a very important practical significance.

HMPTrimetazidineheart failureischemic heart disease in elderly

谢凌云

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重庆医科大学附属第一医院 重庆 400016

麝香保心丸 曲美他嗪 心力衰竭 老年缺血性心肌病

2015

延边医学

延边医学

ISSN:
年,卷(期):2015.(7)
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