摘要
目的：探究脓毒症患者的白细胞计数、血清降钙素原和C-反应蛋白的动态变化，以提高其诊断和预后价值。方法：择取2012年1月-2014年12月入住本院进行治疗的脓毒症患儿与身体健康的患儿各90例，分为脓毒症组与正常组，为两组患儿抽取2ml血液，并对患儿血液中的白细胞计数(WBC）、血清降钙素原（PCT）和C-反应蛋白（CRP）进行动态检测。结果：经过检测，脓毒症组的90例患儿，其WBC、PCT、CRP的阳性标准均远远高于正常组，PCT尤其明显，P＜0．05，差异具有统计学价值。结论：WBC、PCT、CRP的动态监测有助于儿科脓毒症的诊断，而PCT数值的高低与脓毒症的轻重程度关系更加密切，临床上可以根据患儿PCT水平的变化判断脓毒症的轻重，以便进行对症治疗。
Abstract
Objective:To explore the white blood cell count in patients with sepsis and dynamic changes of serum procalcitonin and C- reactive protein, in order to improve their diagnostic and prognostic value. Methods:January 2012 choose to take in children with sepsis in children with healthy- 2014 December hospital stay for treatment of all 90 cases were divided into sepsis group and the normal group, children with two extraction 2ml blood, and children with blood leukocyte count (WBC), serum procalcitonin (PCT) and C-reactive protein (CRP) for dynamic testing. Results:After testing, 90 cases of children with sepsis group, the WBC, CRP, PCT positive standard were much higher than the normal group, PCT is particularly evident, P<0.05, the difference was statistically significant.Con-clusion: The dynamic monitoring WBC, CRP, PCT helps diagnose pediatric sepsis, while the relationship between severity of PCT values more closely correlated with sepsis, sepsis can be judged according to changes in PCT levels in children with clinical y severity, for symptomatic treatment.
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