摘要
目的：观察人参提取物Rb1成分对增生性瘢痕的作用。方法：选取十分成熟的兔耳增生性瘢痕模型，每只耳朵做3处增生性瘢痕，每个瘢痕做不同处理：空白对照组（a），生理盐水注射组(b)，人参提取物组(c )。测定Masson染色，胶原含量，免疫组织化学上相关胶原Ⅰ型蛋白表达。结果：人参Rb1组瘢痕增生程度轻、胶原含量下降、Ⅰ型胶原蛋白表达低。结论：Rb1可以抑制增生性瘢痕的发展。
Abstract
Objective To study the effect of ginseng extract Rb1 component on hypertrophic scars, providing a new method for the treatment of hypertrophic scars. Methods Select a very mature hypertrophic scar model rabbit ears, do three in each ear hypertrophic scars, scars do each different treatment:control group (a), saline injection group (b), ginseng extract (c). To subject the Masson staining, collagen determination and chemical related expression of immunohistochemistry protein col agen type 1 in each group. Results The Masson staining, collagen determination and chemical related expression of immunohistochemistry protein collagen type 1 in Rb1 group were lower than the other groups. Conclusion The Rb1 can inhibit the development of hypertrophic scars.
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