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人参提取物Rb1对瘢痕增生的作用

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目的:观察人参提取物Rb1成分对增生性瘢痕的作用。方法:选取十分成熟的兔耳增生性瘢痕模型,每只耳朵做3处增生性瘢痕,每个瘢痕做不同处理:空白对照组(a),生理盐水注射组(b),人参提取物组(c )。测定Masson染色,胶原含量,免疫组织化学上相关胶原Ⅰ型蛋白表达。结果:人参Rb1组瘢痕增生程度轻、胶原含量下降、Ⅰ型胶原蛋白表达低。结论:Rb1可以抑制增生性瘢痕的发展。
Objective To study the effect of ginseng extract Rb1 component on hypertrophic scars, providing a new method for the treatment of hypertrophic scars. Methods Select a very mature hypertrophic scar model rabbit ears, do three in each ear hypertrophic scars, scars do each different treatment:control group (a), saline injection group (b), ginseng extract (c). To subject the Masson staining, collagen determination and chemical related expression of immunohistochemistry protein col agen type 1 in each group. Results The Masson staining, collagen determination and chemical related expression of immunohistochemistry protein collagen type 1 in Rb1 group were lower than the other groups. Conclusion The Rb1 can inhibit the development of hypertrophic scars.

ginseng extractscaranimal scar model

张克勤、岳毅刚、李昕珊

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广西壮族自治区南溪山医院整形外科广西 桂林 541002

广西壮族自治区桂林医学院附属医院整形外科 广西 桂林 541002

人参提取物 瘢痕 动物瘢痕模型

2015

延边医学

延边医学

ISSN:
年,卷(期):2015.(8)
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