Objective:To investigate the clinical efficacy of neoadjuvant chemotherapy for advanced ovarian cancer. Methods:32 cases of the use of neoadjuvant chemotherapy for patients with advanced ovarian cancer in our hospital from June 2011 to December 2013 were treated as the observation group, another 32 patients were treated with traditional chemotherapy in the treatment of advanced ovarian cancer patients as the control group, the clinical effects and toxicities of these two grops were observed and compared. Results:The pa-tients in complete remission in 16 cases, 10 cases of partial remission, stable disease in 4 cases, progress2 cases, the total effective rate was 81.25﹪(26/32). The patients in complete remission in 10 cases, 9 cases of partial remission, stable disease in 7 cases, progress in 6 cases, the total effective rate was 59.38﹪(19/32). Two groups, P<0.05 significant difference was statistically significant;groups toxicities were nausea, vomiting, diarrhea and other gastrointestinal reactions and hair loss, neurological toxicity based, no serious systemic allergic reac-tion occurs Al patients could tolerate. Conclusion:The clinical efficacy of neoadjuvant chemotherapy for advanced ovarian cancer, mild side effects, patients can tolerate, worthy of clinical application.
NETL
NSTL
万方数据
