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急性胰腺炎乌司他丁治疗的临床疗效研究

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目的:分析急性胰腺炎乌司他丁治疗的临床疗效。方法:选取本院收治的60例急性胰腺炎临床资料,随机分为治疗组与对照组,各30例。对照组采取常规治疗,治疗组实施乌司他丁治疗,对比两组患者临床疗效。结果:治疗组总有效率为93.33%明显高于对照组的76.67%,差异有统计学意义(P<0.05)。治疗组腹痛缓解时间、胰腺水肿消失时间、首次主动排便时间均明显短于对照组,差异有统计学意义(P<0.05)。治疗组治疗后CRP、TNF- a、IL-15、IL-10等水平明显低于对照组,差异有统计学意义(P<0.05)。治疗组不良反应发生率为6.67%明显低于对照组的20.00%,差异有统计学意义(P<0.05)。结论:乌司他丁治疗急性胰腺炎,疗效安全,充分改善炎症因子水平,有效控制病情发展,降低不良反应发生率,值得临床推广。
objective:to analysis the clinical curative effect of ulinastatin treatment of acute pancreatitis. Selection methods:clinical data of 60 patients admitted in our hospital with acute pancreatitis, randomly divided into treatment group and control group, 30 cases each. , control group treated with conventional treatment group implementation of ulinastatin treatment, compared two groups of pa-tients with clinical efficacy. Results:treatment group total effective rate of 93.33%is significantly higher than the control group 76.67%, the difference was statistically significant (P<0.05). Treatment group abdominal pain relief time, pancreatic edema disappeared, active for the first time defecation time were significantly shorter than the control group, the difference was statistically significant (P<0.05). CRP, TNF- a group after treatment, IL- 15, IL- 10 levels significantly lower than the control group, the difference was statistically significant (P<0.05). CRP, TNF- a group after treatment, IL- 15, IL- 10 levels significantly lower than the control group, the dif-ference was statistically significant (P< 0.05). The incidence of adverse reactions was 6.67% treatment group was obviously less than 20.00%in the control group, the difference was statistically significant (P<0.05). Conclusion:ulinastatin treatment of acute pancreatitis, curative effect of safety, fully improve the inflammatory factor levels, effective control of the disease, reduce the incidence of adverse re-actions, worthy of clinical promotion.

acute pancreatitisUlinastatin. Clinical curative effect

吴彦彦、李丽平、靳淑黎

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河南省濮阳市安阳地区医院 455000

急性胰腺炎 乌司他丁 临床疗效

2015

延边医学

延边医学

ISSN:
年,卷(期):2015.(9)
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