Objective To observe the effects of dexmedetomidine efficacy and safety in open liver tumorresection operation in pa-tientswith generalanesthesia. Methods elective abdominal operation patients with liver tumorresectionin60 cases, age 30 ~65 years old, ASAI ~ IIIgrade, wererandomlydividedintotwo groups, anesthesia wasinducedandmaintained with propofolrespectively (groupP) and dexmedetomidine (groupD), andallofthemwereinhaled seven sevoflurane. Changesin MAPandHR patientsduring theobservationan-drecordingofanesthesia,adversereactions andirritability, andothercircumstances ofrecoverytimeand look attheendoftheoperation.Results compared with those beforeanesthesia, P group, MAP decreased significantly before tracheal intubation, after tracheal intubation and ex-tubationwere significantly higher (P<0.05), significant changes in group D MAP no, after induction of anesthesia in group D HR is significantly slower (P<0.05), P groupHR only after intubation andextubation before significantlyfaster (P<0.05),restless P groupafter-operation 2patients afteroperation,Dgrouphadnoobviousadversereaction.Conclusiondexmedetomidine for open liver tumorresection pa-tients, heartrate, bloodpressure stable, wakeup intime,postoperative agitation and other less adverse reaction.
NETL
NSTL
万方数据
