Observe the effects of the PRP combined with autologous bone used to repair the defects of rabbits radius.To discuss the mechanism of action of PRP used to repair the defects rabbit radius,and provide the experimental evidence on PRP combined with autologous bone used to repair the defects of rabbits radiusMethods: Use the adult New Zealand rabbits as experimental subjects, resect 1.5 cmradius shaft to make the nonunion animal model, without internal fixation and external fixation. One side filled with autogenous bone, the other side filled with autogenous bone combined with PRP. In 2 weeks, 4 weeks, 8 weeks, 12 weeks after the operation , rabbits are observed with specimens of radius, x-ray observation on defects of bone formation, and the specimens obseved with light microscope observation of pathology after H-E staining.Results: All the observations have proved that PRPcombined with autogenous bone graft to repair the nonunion isbetter than autogenous bone graft alone.Conclusion: The effects of PRP combined with autogenous bone to repair the nonunion is better than autologous bone graft alone,and It provide a theoretical basis on clinical application.
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