摘要
目的::探讨阿尔茨海默病患者血清胱抑素C水平的变化。方法:选择2013年1月至2014年6月住本:的阿尔茨海默病患者61例以及年龄、性别相匹配的健康老年人64例,以全自动生化分析仪分别检测两组血清胱抑素C水平。结果:阿尔茨海默病组血清胱抑素C (0.96±0.37mg/l)水平降低,与对照组(1.09±0.29mg/l)比较,差异有统计学意义(P<0.05)。结论:阿尔茨海默病患者血清胱抑素C水平降低,其保护机制有待进一步研究。
Abstract
Objective:To explore the alterations of serum cystatin C in patients with Alzheimer’s disease.Methods:61 inpatients with Alzheimer’s disease and 64 healthy elders matching with age and gender were enrol ed from Jan 2013 to Jun 2011, the level of serum cystatin C was measured by automatic biochemistry analyzer in the two groups. Results:The level of serum cystatin C(0.96±0.37mg/l) significantly decreased in AD group, comparing with the control group(1.09± 0.29mg/l), the dif erence was significant(P<0.05).Conclusion:The level of serum cystatin C decreased,However,the mechanism needs further study.