摘要
目的：探讨高频震荡通气（HFOV)治疗新生儿呼吸窘迫综合症的临床疗效与安全性。方法：选取我院需机械通气的新生儿呼吸窘迫综合症患儿78例，将其随机分为观察组和对照组，每组各39例，观察组采用高频震荡通气（HFOV)治疗，对照组采用常频机械通气（CMV）治疗，比较两组患儿吸氧时间、机械通气时间、住院时间及不同时间血气分析变化。结果：观察组机械通气时间、吸氧时间及住院时间均明显短于对照组，两组比较差异具有统计学意义，P<0.01，且两组患儿不同时间血气分析变化也有明显差异，P<0.01。结论：HFOV治疗新生儿呼吸窘迫综合症可有效缩短机械通气时间、吸氧时间，改善患儿肺氧合功能，降低死亡率，是一种安全性高的治疗新生儿呼吸窘迫综合症的机械通气方法。
Abstract
objective to investigate the high frequency oscil ation ventilation (HFOV) the clinical curative effect and security of the treatment of neonatal respiratory distress syndrome. Methods select our hospital need mechanical ventilation in neonatal respiratory distress syndrome in 78 cases, which were randomly divided into observation group and control group, each group of 39 cases of observation group was treated using high frequency oscil ation ventilation (HFOV), control group adopts Chang Pin mechanical ventilation (CMV) treatment, compared two groups of children with oxygen time, mechanical ventilation time, length of hospital stay and the change of blood gas analysis in different time. Results observation group mechanical ventilation, oxygen time and hospital stay time were significantly shorter than the control group, two groups of comparison difference is statistical y significant, P<0.01, blood gas analysis and two groups of children with dif erent time changes also have obvious difference, P<0.01). Conclusion HFOV treatment of neonatal respiratory distress syndrome can effectively shorten the time of mechanical ventilation and oxygen therapy time, children improve pulmonary oxygenation function, reduce mortality, is a kind of high safety me-chanical ventilation method for the treatment of neonatal respiratory distress syndrome.
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