Objective:to analyze the application details in nursing in operation room nursing. Method:choose the take operation therapypatients from 2014 March-2015 year in March admitted 100 cases, were randomly divided into control group (50) and nursing group (50), the control group received routine nursing care, nurs-ing group adopted in details on the basis of routine nursing care, compared two groups of patients' satisfaction with nursing care. Results:the nursing group satisfaction is 94%, the control group of satisfaction is 80%, the nursing group was significantly better than the control group (P<0.05). Conclusion:the details of care is safe and effective, can enhance patient satisfaction, promote therecovery of patients.