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免疫相关分子联合测定在结核性胸膜炎诊断中的应用研究

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目的:研究结核性胸膜炎运用免疫相关分子联合测定的临床效果。方法:我院选择2012年4月~2014年4月间诊治的100例结核性胸膜炎患者,将其作为观察组。80例非结核性胸腔积液患者,将其作为对照组。对其积液ADA活性、IFN- r含量以及PPD试验阳性率,对结核性胸膜炎的各项指标的特异性和灵敏度进行评价。结果:通过对两组患者进行比较,观察组患者的ADA活性、IFN- r含量以及PPD试验阳性率明显比对照组高,两组患者差异显著,有统计学意义(P<0.05);结核性胸膜炎运用3项指标联合检测明显比单项检测及其中任何2项的诊断特异度和灵敏度高,差异显著,有统计学意义(P<0.05)。结论:在对结核性胸膜炎诊断的过程中运用多指标联合检测具有很好的临床价值,能够有效的提升诊断阳性率。
To study the clinical effect of tuberculous pleurisy by combined determination of immune related molecules. Methods:select 100 cases in our hospital in patients with tuberculous pleurisy in 2012 April~2014 year in April diagnosis and treatment as the observation group, the. 80 cases of non tuberculous pleural ef-fusion patients, as the control group. The ADA activity, IFN-r content and effusion PPD test positive rate, evaluated the indicators of tuberculous pleurisy specificity and sensitivity. Results:the two groups of patients were compared in the observation group, ADA activity, IFN-r content and PPD test positive rate was significantly higher than the control group, the differences between the two groups were significant, with statistical significance (P<0.05);tuberculous pleurisy by combined detec-tion of 3 indexes were compared with single detection and any of these 2 items of diagnosis specificity and high sensitivity, significant difference was statistically sig-nificant (P<0.05). Conclusion:the use of multiple combined detection indexes in diagnosis of tuberculous pleurisy in clinical value is very good, can effectively im-prove the diagnostic positive rate.

ADA activityIFN-r contentthe positive rate of PPD testtuberculous pleurisyApplication Research

段月庭、王国英

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青岛大学医学院 山东青岛 266071

ADA活性 IFN- r含量 PPD试验阳性率 结核性胸膜炎 应用研究

2015

延边医学

延边医学

ISSN:
年,卷(期):2015.(14)
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