Transcription is the process by which genetic information is copied from DNA to RNA,and it can be divided into three stages:transcription initiation,elongation,and termination.Transcription termination is the last step of gene transcription and is crucial for accurate gene expression.Two prevailing modes of transcription termination exist in bacteria:Rho-dependent termination and intrinsic termination(Rho-independent termination).Transcription termination is positively and negatively regulated by bacterial or bacteriophage proteins.In this review,we summarize the research progress of bacterial transcription and its regulation,with the aim of providing a theoretical foundation for further studies and understanding of transcription termination process.
维普
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