首页|中国五个民族STR位点遗传多态性(2)

中国五个民族STR位点遗传多态性(2)

STR Polymorphisms in Five Chinese Ethnic Groups(2)

扫码查看
通过对我国汉回蒙藏维5个民族的50个家系和500份样本的STR基因扫描、基因分型和遗传结构分析,获得了STR基因传递方式及遗传特征的大量科学数据。研究结果表明在9个STR位点上汉族有60种STR等位基因,149种基因型;回族有63种STR等位基因,144种基因型;蒙古族有69种STR等位基因,173种基因型;藏族有77种等位基因,168种基因型;维吾尔族有70种STR等位基因,148种基因型。中国5个民族的数据与美籍黑人,美国高加索人群相比较发现彼此有显著的差异,而中国5个民族之间的差异不显著。
Population genetic studies were performed in Chinese Han, Hui, Mongolian,Tibetan and Uygur. Allele frequency distributions were analyzed for ten loci, i e, D3S1358, VWA, CSF1PO, FGA, THO1, TPOX,. D5S818,D13S317 and D7S820 by GeneScan. The results showed that there were 60 STR alleles and 149 genotypes in Han; 63 STR alleles and 144 genotypes in Hui; 69 STR alleles and 173 genotypes in Mongolian; 77 STR alleles and 168 genotypes in Tibetan; 70 STR alleles and 148 genotypes in Uygur. Significant differences were identified among ethnic groups (African-American, US-Caucasian and Chinese-Oriental), but similarity was found among the five Chinese populations, and immunogenomics and phammacogenomics studied in this report. These findings indicated that the nine STR loci and amelogenin locus were very useful for individual identification in forensic science.

STR polymorphismChinese nationalitygenetic databank

李生斌、汪健、杨焕明、赖江华、高树辉、郑海波、李双顶、冯成博、金天博、冯继东、赵建民

展开 >

中国科学院遗传研究所人类基因组中心, 北京 100101

西安交通大学部级法医学重点实验室, 西安 710061

中国农业大学生物技术国家重点实验室, 北京 100094

西藏民族学院, 咸阳 710000

展开 >

STR多态性 中华民族 遗传数据

国家自然科学基金

39670399,39200141

2000

遗传学报
中国遗传学会 中国科学院遗传与发育生物学研究所

遗传学报

CSTPCDCSCD北大核心
影响因子:0.821
ISSN:1673-8527
年,卷(期):2000.27(12)
  • 46
  • 5