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不同性别患者精神分裂症症状与健康相关的生命质量比较

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目的:检验精神分裂症患者的HRQoL是否存在性别差异,并探讨性别与精神分裂症症状和HRQoL之间的关系.方法:选择2020年6月至2022年4月来本院门诊接受治疗的1315名精神分裂症患者为研究对象,用PANSS量表进行症状评估,用SF-36、EQ-5D及SQLS进行HRQoL相关评估,并对影响HRQoL的症状的性别差异进行比较.结果:PANSS焦虑抑郁症状、阳性症状、阴性症状与HRQoL之间的相关性较高.女性中,较高的阴性症状评分和焦虑抑郁症状评分与较高的SQLS、较低的SF-36、EQ-5D评分相关;在男性中,较高的阳性症状评分和焦虑抑郁症状评分与较高的SQLS、较低的SF-36、EQ-5D评分相关.结论:男性精神分裂症患者的HRQoL要高于女性.阴性症状、焦虑抑郁症状对女性HRQoL影响较大,阳性症状、焦虑抑郁症状对男性HRQoL影响较大.
Comparison of Symptoms and Health-related Quality of Life in Patients with Schizophrenia of Different Genders
Objective:To examine whether there are gender differences in HRQoL in patients with schizophrenia,and to explore the relationship between gender and symptoms of schizophrenia and HRQoL Method:1315 schizophrenia patients who received treatment in our outpatient department from June 2020 to April 2022 were selected as the re-search subjects.Use PANSS scale for symptom assessment,SF-36,EQ-5D,and SQLS for HRQoL related as-sessment,and compare gender differences in symptoms that affect HRQoL Result:There is a high correlation be-tween PANSS anxiety and depression symptoms,positive symptoms,negative symptoms,and HRQoL Among women,higher negative symptom scores and anxiety and depression symptom scores are associated with higher SQLS,lower SF-36,and EQ-5D scores.In males,higher positive symptom scores and anxiety and depression symptom scores are associated with higher SQLS,lower SF-36,and EQ-5D scores.Conclusion:The HRQoL of male patients with schizophrenia is higher than that of females.Negative symptoms,anxiety and depression symptoms have a greater impact on female HRQoL,while positive symptoms,anxiety and depression symptoms have a greater impact on male HRQoL

schizophreniagenderhealth related quality of life

李彦、廖波、李青芸、方巧、张文青

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宜春市第三人民医院 精神科,江西 宜春 336000

精神分裂症 性别 健康相关的生命质量

江西省卫生健康委普通科技计划

202212629

2024

宜春学院学报
宜春学院

宜春学院学报

影响因子:0.271
ISSN:1671-380X
年,卷(期):2024.46(3)
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