Progress of Nanoparticles Drug Delivery System in the Treatment of Liver Fibrosis
Liver fibrosis is a sign of early onset of liver disease.Acute and chronic liver injury or inflammation can lead to liver fibrosis,which already occurs before the more serious stages of cirrhosis and liver cancer.However,there are no better clinical treatments and specific drugs for liver fibrosis.Nanocarriers can improve drug metabo-lism and distribution,enhance drug targeting and achieve better therapeutic effects by virtue of the physical and chemical properties of the material itself and functional modification of the nanocarrier surface.This paper summa-rizes the application of nanocarriers in the treatment of liver fibrosis,and provides a theoretical basis for the con-struction of safe and effective nanoparticles drug delivery systems for the efficient treatment of liver fibrosis in the clinic.
nanoparticles drug delivery systemliver fibrosishepatic stellate cellsactive targeting
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