首页|25羟维生素D与儿童喘息性支气管炎发病及病情严重程度相关性研究

25羟维生素D与儿童喘息性支气管炎发病及病情严重程度相关性研究

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目的:探讨25羟维生素D水平与儿童喘息性支气管炎发病及病情严重程度相关性.方法:回顾性分析新余市人民医院儿内科病房2021年1月-2022年12月收治的60例儿童喘息性支气管炎患儿临床资料,根据其病情严重程度分为喘支轻度组(28例)、喘支中重度组(32例).同期选取健康体检的就诊儿童30例,设定为对照组.采集和对比各组的血测25羟维生素D值,分析25羟维生素D与该病发病及病情严重程度的相关性.结果:对照组、喘支轻度组、喘支中重度组25羟维生素D水平呈降低趋势,免疫球蛋白E、白细胞介素-6水平呈递增趋势(P<0.05).Pear-son相关分析显示,25羟维生素D水平与喘支轻度、喘支中重度呈负相关(r=-0.482、-0.571,P=0.018、0.011)结论:25羟维生素D缺乏可能会导致儿童喘息性支气管炎发生,监测该指标,可有助于该疾病诊断,并评估病情严重程度.
A Correlation Study Between the 25 Hydroxyvitamin D and the Severity of the Asthmatic Bronchitis in Children
Objective:To explore the correlation between the level of 25 hydroxy vitamin D and the severity of asth-matic bronchitis in children.Method:Retrospective analysis was used in the clinical data of 60 children with asth-matic bronchitis admitted to the pediatric internal medicine ward of Xinyu People's Hospital from January 2021 to December 2022.According to the severity of the condition,it was divided into a mild asthma group(28 cases)and a moderate-severe asthma group(32 cases).During the same period,the study selected 30 children who received medical examinations as the control group.We collected and compared the 25 hydroxyvitamin D values in the blood of each group,and analyzed the correlation between 25 hydroxyvitamin D and the severity of the condi-tion.Result:The levels of 25 hydroxyvitamin D in the control group,mild asthma group,and moderate-severe asthma group showed a decreasing trend,while the levels of immunoglobulin E and interleukin-6 showed an in-creasing trend(P<0.05).Pearson correlation analysis showed a negative correlation between 25 hydroxyvitamin D levels and mild asthma group and moderate-severe asthma group.Conclusion:A deficiency of 25 hydroxyvita-min D may lead to the development of asthmatic bronchitis in children.Monitoring this indicator can help diagnose and evaluate the severity of asthma bronchitis.

childrenasthmatic bronchitis25 hydroxyvitamin Dcorrelation

蒋玲

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新余市人民医院 儿内科,江西 新余 338000

儿童 喘息性支气管炎 25羟维生素D 相关性

2024

宜春学院学报
宜春学院

宜春学院学报

影响因子:0.271
ISSN:1671-380X
年,卷(期):2024.46(6)