Analysis of the Risk Factors of Incision Infection After Laparoscopic Cholecystectomy and the Effect of Prophylactic Antibiotics on the Incision Infection Rate
Objective:To determine the effectiveness of antibiotics in preventing postoperative infection after laparo-scopic cholecystectomy and the risk factors of postoperative infection.Methods:464 patients who underwent laparo-scopic cholecystectomy in our hospital between January 2022 and December 2023 were collected.In the antibiotic group,260 patients were routinely given first or second generation cephalosporins after induction of anesthesia.In the non-antibiotic group,204 patients were not given prophylactic antibiotic therapy.The basic demographic data and postoperative infection were compared and analyzed.Results:The total postoperative infection rate of 464 patients was 2.4％.There was no statistical significance in the incidence of postoperative infection between the two groups(P=0.474).Among 260 patients in the antibiotic group,5 patients(2.0％)were infected,while among 204 patients in the no-antibiotic group,6 patients(3.0％)were infected.The risk factors for postoperative infection were advanced age(P=0.001),low albumin(P=0.010),long hospital stay(P=0.000),and long operation time(P=0.002).Binary logistic regression analysis showed that age and length of stay had significant influence on postoperative infection.For every 1-year increase in age,the risk of postoperative infection increases by 1.08 times.For each additional day spent in hospital,the risk increased 1.33 times.Conclusions:Prophylactic antibiotic use does not reduce the incidence of incision infection after laparoscopic cholecystectomy,but prophylactic antibiot-ic use should be considered in patients with high risk factors such as older age and longer hospital stay.
万方数据
维普
