The Affiliated Nanhua Hospital and School of Basic Medical Sciences,Hengyang Medical School,University of South China,Hengyang,Hunan 421001,China

School of Laboratory Medicine and Life Sciences,Wenzhou Medical University,Wenzhou,Zhejiang 325035,China

National Health Commission Key Laboratory of Birth Defect Research and Prevention,Hunan Provincial Maternal and Child Health Care Hospital,Changsha,Hunan 410008,China

Key Laboratory of Ministry of Education for TCM Viscera-State Theory and Applications,Ministry of Education of China,Liaoning University of Traditional Chinese Medicine,Shenyang,Liaoning 110847,China

Key Laboratory of Diagnosis and Treatment of Severe Hepato-Pancreatic Diseases of Zhejiang Province,The First Affiliated Hospital of Wenzhou Medical University,Wenzhou,Zhejiang,China

Hubei Key Laboratory of Cell Homeostasis,College of Life Sciences,Wuhan University,Wuhan,Hubei 430072,China

Nanjing Maternity and Child Health Care Hospital,Obstetrics and Gynecology Hospital Affiliated to Nanjing Medical University,Nanjing 210004,China

Animal Center,Wenzhou Medical University,Wenzhou,Zhejiang 325035,China

Department of Cardiology,The First Affiliated Hospital of University of South China,Hengyang,Hunan,China

School of Life Science and Technology,Shanghai Tech University,Shanghai 201210,China

Department of Microbiology,Biochemistry and Molecular Genetics,New Jersey Medical School-Rutgers,The State University of New Jersey,Newark,NJ,USA

State Key Laboratory of Pharmaceutical Biotechnology,Department of Cardiology,Nanjing Drum Tower Hospital,The Affiliated Hospital of Nanjing University Medical School and MOE Key Laboratory of Model Animal for Disease Study,Model Animal Research Center,Nanjing University,Nanjing 210061,China