Application of Deep-Eutectic Solvents in Green Organic Synthesis
Since the definition of "green chemistry" was proposed in 1991,the green solvents have attracted considerable attention.In the two decades ago,ionic liquids grew up.However,as following the research,it was found that ionic liquids had some drawbacks.Nowadays,some new types of low-transition-temperature mixtures,i.e.deep-eutectic solvents (DES) are raised.Compared with the traditional ionic liquids,deep-eutectic solvents are greener,cheaper and more accessible.Furthermore,the preparation methods of deep-eutectic solvents are easy,and the components of them are biodegradable.In recent years,deep-eutectic solvents have been applied as green solvents in organic synthesis widely.In this review,the application of deep-eutectic solvents in cyclization reactions,replacement reactions,addition reactions,multicomponent reactions,enzyme catalytic reactions and other reactions in the last few years are briefly summarized,and the prospects of DESs are also discussed.
NETL
NSTL
万方数据
维普
