Recent Advances in Visible-Light-Induced C(3)—H Functionalization of Quinoxalinones under Transition-Metal-Free or Photocatalyst-Free
Quinoxalinone and its derivatives are significant non-aromatic heterocycles existing in various bioactive natural products,pharmaceuticals,and functional materials,and exhibit an impressive spectrum of important biological properties.In recent years,the functionalization of quinoxalinones has attracted extensive attention of chemical workers,and important progress has made in the construction of C-3 substituted quinoxalinones by C—H functionalization.Photoredox catalysis has been widely used in the synthesis and conversions of organic compounds,because it can generate high reactive free radical intermediates under mild conditions using green and clean energy.Thus,photocatalysis synthesis is becoming powerful tools for C—H functionalization of quinoxalinone.This photocatalytic reactions under transition-metal-free or photocatalyst-free conditions meet the requirements of green chemistry and sustainable development,which have become a powerful tool for the functionalization of quinoxalinones and attracted the attention of many scholars.The research progress of C(3)—H functional-ization of quinoxalinones by visible-light photoredox catalysis under transition-metal-free or photocatalyst-free conditions is reviewed during the past five years.The reaction mechanisms are systematically discussed,and the challenges and opportuni-ties of this field are included.
NETL
NSTL
万方数据
