Rhodium(Ⅲ)-Catalyzed Synthesis of CF3-1H-benzo[de][1,8]naph-thyridines via C—H Activation/Annulation of Benzimidates and CF3-Imidoyl Sulfoxonium Ylides
A rhodium-catalyzed C—H activation/annulation domino reaction of benzimidates and CF3-imidoyl sulfoxonium ylides has been achieved.This synthetic strategy has good functional groups tolerance and universality of substrates,and a series of trifluoromethyl-containing lH-benzo[de][1,8]naphthyridines were synthesized in 22％～86％yields.
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