巢式-碳硼烷硼氢键官能化反应研究进展
Recent Progress in B—H Bond Functionalization of nido-Carboranes
付雅彤 1孙超凡 1张丹 1金成国 1陆居有2
作者信息
- 1. 宜宾学院材料与化学工程学部 四川宜宾 644000
- 2. 海南大学化学化工学院 海口 570228
- 折叠
摘要
巢式-碳硼烷是医学、材料科学和有机金属/配位化学等领域中多功能的重要砌块.近年来,巢式-碳硼烷的硼氢键直接活化及官能化反应受到了广泛关注.由于碳硼烷通常含有十个化学环境相似的硼氢键,因此区域选择控制一直是碳硼烷硼氢键活化的一个长期挑战.近年来,巢式-碳硼烷开口平面上的硼氢键官能化取得了重大进展,而非开口球面上的硼氢键选择性活化依然具有挑战性.总结了巢式-碳硼烷的区域选择性硼氢键官能化反应的研究进展,从开口面和非开口面硼氢键活化两个角度进行梳理.
Abstract
nido-Carboranes are versatile building blocks in medicine,materials science,and organometallic/coordination chemistry.Recently,direct B—H activation and functionalization of nido-carboranes have received much attention.Achieving regioselectivity in polyhedral cage B—H activation among ten chemically similar B—H vertices is a long-standing challenge in carborane chemistry.In this context,the activation of exo-cage B—H vertices on the open C2B3 pentagonal plane of nido-carboranes has been extensively studied.However,few direct activation reactions of B—H vertices that are located on the closed polyhedral sphere in nido-carborane have been reported.The recent progress on the regioselective B—H bond function-alization reaction of nido-carboranes is summarized.This topic is categorized into open plane exo-B—H activation and poly-hedral sphere B—H activation.
关键词
碳硼烷/硼氢键活化/区域选择性/官能化/导向基团Key words
carboranes/B—H bond activation/regioselectivity/functionalization/directing group引用本文复制引用
基金项目
国家自然科学基金(22161015)
海南省自然科学基金(221RC448)
出版年
2024
NETL
NSTL
万方数据