Recent Progress in Electrochemical Modification of Amino Acids and Peptides
With the increasing importance of peptides in the treatment of oncological diseases and biomedical applications,the development and construction of new methods for peptide molecules have become a hot research topic for organic synthetic chemists.As a green and efficient reaction tool,organic electrochemistry has been gradually utilized in the field of organic small molecule synthesis in recent years,and its mild and controllable features are suitable for solving the chemo-and regioselectivity problems of the existing bioconjugation strategies,which provide an important synthetic means for the selective modification of peptide molecules.The electrochemical approaches to amino acids and peptides modification devel-oped in the last five years are reviewed,and the distinct advantages of electrochemical synthesis techniques and its applicabil-ity in the development of novel biocompatible methodologies are described.
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