Electrochemical Enabled Phosphorylation of α-Diazoester to Access Phosphinic Hydrazone
The phosphonic hydrazone represents a rare molecular fragment with promising applications in the fields of phar-maceuticals,functional materials,ligands,and synthetic intermediates.A novel electrochemical approach is presented for the generation of Ni2+ions from sacrificial anode nickel,facilitating the phosphorylation of α-diazoester to construct phosphite hydrazone.The reaction was performed in an undivided cell in absence of precious metal catalyst and chemical redox reagent,exhibiting good substrate applicability.The mechanistic investigation has confirmed the predominant role of paired electrolysis in mediating the catalytic mechanism.
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