Palladium-Catalyzed C(sp3)—Si Bonds Transformation for Constructing Trifluoropropyl(Hetero)arenes through C(sp3)—C(sp2)Cross-Coupling Reactions
Palladium-catalyzed C(sp3)—Si bonds transformation of commercially available polyalkoxy trifluorosilane reagents has been developed through C(sp3)—C(sp2)cross-coupling reactions.This Hiyama cross-coupling reaction shows good functional group tolerance and provides a series of trifluoropropyl(hetero)arenes.The fluoride source and alkyl tether of bisphosphine ligand play important roles in improving yields.
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