Research Progress of Continuous Flow Selective Hydrogenation Technology
Flow hydrogenation technology is an important means of synthesizing and preparing fine chemicals,accounting for a significant proportion of the preparation of pharmaceutical intermediates and the production of high-value chemicals.The heterogeneous catalytic hydrogenation method has excellent economic and environmental protection properties.By using loaded catalysts,pollutant emissions can be effectively reduced,and substrate conversion rate and selectivity can be improved.This article provides a detailed introduction to the types of microreactors classified by catalyst loading methods and commonly used solid catalysts and elaborates on the progress made by continuous flow technology in the field of catalytic hydrogenation of different functional groups.On this basis,flow chemistry,as one of the top ten emerging chemical technologies,has great prospects in catalytic hydrogenation applications.Continuous,automated,and intelligent technologies are the future of the pharmaceutical and chemical industries.