首页|连续流选择性加氢技术研究进展

连续流选择性加氢技术研究进展

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流动氢化技术是合成制备精细化学品的重要手段,在制备药物中间体及生产高值化学品方面占比极大。非均相催化氢化法具有优良的经济环保性,通过使用负载型催化剂能有效减少污染物排放,提高底物转化率以及选择性。详细介绍了按催化剂负载方式分类的微反应器类型以及常用的固体催化剂,阐述了连续流技术在不同官能团催化氢化领域中取得的进展。在此基础上概述了作为十大新兴化学技术之一的流动化学,在催化加氢应用上具有极大远景,连续、自动化和智能化技术是制药和化学工业的未来。
Research Progress of Continuous Flow Selective Hydrogenation Technology
Flow hydrogenation technology is an important means of synthesizing and preparing fine chemicals,accounting for a significant proportion of the preparation of pharmaceutical intermediates and the production of high-value chemicals.The heterogeneous catalytic hydrogenation method has excellent economic and environmental protection properties.By using loaded catalysts,pollutant emissions can be effectively reduced,and substrate conversion rate and selectivity can be improved.This article provides a detailed introduction to the types of microreactors classified by catalyst loading methods and commonly used solid catalysts and elaborates on the progress made by continuous flow technology in the field of catalytic hydrogenation of different functional groups.On this basis,flow chemistry,as one of the top ten emerging chemical technologies,has great prospects in catalytic hydrogenation applications.Continuous,automated,and intelligent technologies are the future of the pharmaceutical and chemical industries.

hydrogenationheterogeneous catalysisflow chemistrymicroreactor

密思怡、马隆龙、刘建国

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东南大学-蒙纳士大学苏州联合研究生院 江苏苏州 215000

东南大学能源与环境学院 南京 210096

氢化 多相催化 流动化学 微反应器

国家自然科学基金中央高校基本科研业务费专项

519762252242022R10058

2024

有机化学
中国化学会,中国科学院上海有机化学研究所

有机化学

CSTPCD北大核心
影响因子:1.09
ISSN:0253-2786
年,卷(期):2024.44(5)