Synthesis of Benzochromenes via Br?nsted Acid Catalyzed Annulation of Naphthol with Propargyl Alcohols
Benzeochromenes,also named as naphthopyrans,are widely found in natural products,bioactive molecules and organic functional materials.A simple and efficient strategy for the synthesis of benzeochromenes with propargyl alcohols andβ-naphthols under mild conditions was developed,and a series of benzeochromenes were prepared in excellent yields.This protocol has the advantages of broad scope,functional group diversity and mild conditions with H2O as the only byproduct.Moreover,ease of operation and gram-scale preparation portend the practical application.
NETL
NSTL
万方数据
