钯催化SO2插入的炔丙基乙酸酯和碘代芳烃的还原偶联反应
Palladium-Catalyzed Reductive Cross-Coupling of Propargyl Acetates with Aryl Iodides Involving the Insertion of SO2
张倩 1应垚璐 1张泓银 1徐林博 1林新奎 1黄晓雷1
作者信息
- 1. 浙江师范大学化学与材料科学学院 先进催化材料教育部重点实验室 浙江金华 321004
- 折叠
摘要
报道了一种高效的钯催化二氧化硫插入的炔丙基乙酸酯和碘代芳烃的还原偶联反应.该反应使用双(二氧化硫)-1,4-二氮杂双环[2.2.2]辛烷加合物(DABSO)作为气态二氧化硫的替代试剂、还原性锰粉作为还原剂,具有反应条件温和、底物范围广、官能团耐受性好等特点.
Abstract
An efficient palladium-catalyzed reductive cross-coupling of propargyl acetates with aryl iodides involving the insertion of sulfur dioxide has been reported.This method employs l,4-diazoniabicyclo[2.2.2]octane-1,4-disulfinate(DABSO)as SO2 surrogate,reductive manganese powder as reductant,and features mild reaction conditions,broad substrate scope and good functional group tolerance.
关键词
钯催化/还原偶联反应/炔丙基乙酸酯/二氧化硫Key words
palladium-catalysis/reductive cross-coupling/propargyl acetates/sulfur dioxide引用本文复制引用
基金项目
国家自然科学基金(22101259)
浙江省自然科学基金(LQ22B020002)
出版年
2024
NETL
NSTL
万方数据