Vinylene Carbonate:A Versatile Synthon in Organic Synthetic Chemistry
In recent years,vinylene carbonate has become a new and ideal multifunctional synthon,which is widely used in a variety of organic transformations.Especially in the field of transition metal-catalyzed C—H functionalization,it can be used to construct target molecules containing carbon and heterocyclic skeletons.Since Nishii and Miura first reported that vinylene carbonate participates in coupling reactions as an"ethynol surrogate"in 2009,it has been successively reported as an"acety-lene surrogate","Cl synthon","acylmethylation reagent",and others.These developments not only highlight the multifunc-tional transformation of vinylene carbonate,but also provide new ideas for the synthesis of complex compounds.The latest research progress of vinylene carbonate in recent years is summarized and the prospects for its future development based on the different reaction roles of vinylene carbonate in synthetic chemistry are proposed.
NETL
NSTL
万方数据
