Research on the genus Streptacidiphilus was mainly focused on the isolation and identification of new species,with relatively less emphasis on the study of secondary metabolites.A new aluminium-complex alumioxamine(3),and two known compounds desferrioxamine E(1)and ferrioxamine E(2)were isolated from the fermentation broth of Streptacidiphi-lus jiangxiensis CGMCC 4.1857.Their structures were elucidated by MS,IR,NMR and single crystal X-ray diffraction tech-nologies.Structurally,compound 3 features aluminum(Ⅲ)as the central atom,which is bonded to six oxygen atoms of the ligand,forming a hexadentate complex.Furthermore,in vitro cytotoxicity assays showed that compound 1 exhibited potential inhibitory activity against four human tumor cell lines(Hela,PANC1,A375 and MHCC-97H)at a concentration of 100 μmol/L with cell viability ranging from 4.8%to 66.4%.