Recent Progress of Aggregation-Induced Emission Materials in Tumor Phototherapy
Cancer is a leading cause of death globally with its incidence rate on the rise.Phototherapy has emerged as a novel approach for precise cancer treatment,offering benefits such as non-invasiveness,no drug resistance,minimal side effects,and ease of operation.Since Prof.Ben Zhong Tang conceptually coined aggregation-induced emission(AIE)in 2001,AIE materials have been extensively applied as efficient photosensitive and photothermal agents.Thanks to their highly twisted molecular structure,AIE materials avoid the issue of π-π stacking in aggregated states,thereby fundamentally addressing the aggregation-caused quenching problem observed in traditional fluorescent materials.This advancement leads to a significant enhancement in quantum yield and photostability.Herein,the author comprehensively reviews the latest applications of AIE materials as photosensitizers,photothermal agents,and diagnostic agents in cancer phototherapy.
NETL
NSTL
万方数据
