A case-control study on risk factors for pancreatic cancer in Baise city and its surrounding areas
Objective To investigate the risk factors for pancreatic cancer in Baise city and its surrounding areas.Methods This study retrospectively analyzed the clinical data of 269 patients diagnosed with pancreatic cancer with complete medical records in the Affiliated Hospital of Youjiang Medical University for Nationalities from January 2015 to June 2023 and the data of 332 patients who were hospitalized with abdominal discomfort and excluded as having tumor disease during the same period.Univariate and multivariate Logistic regression were adopted to analyze the data on their gender,age,body mass index,smoking history,drinking history,hypertension history,diabetes history,hepatitis B virus infection history,Helicobacter pylori infection histo-ry,blood lipid status,biliary disease history,chronic pancreatitis history,family history and genetic history,so as to find independent risk factors for pancreatic cancer.Results Univariate analysis showed that smoking history,drinking history,hypertension history,diabetes history,hepatitis B virus infection history,Helico-bacter pylori infection history,hyperlipidemia,chronic pancreatitis history and biliary disease history were risk factors for pancreatic cancer.Multivariate analysis showed that smoking history(OR=2.972),hypertension history(OR=5.279),diabetes history(OR=35.819),Helicobacter pylori infection history(OR=24.999),hyperlipidemia(OR=12.665),biliary disease history(OR=16.611)were independent risk factors for pancreatic cancer.Conclusion The possible risk factors of pancreatic cancer in this area are smoking his-tory,hypertension history,diabetes history,Helicobacter pylori infection history,hyperlipidemia and biliary disease history.By guiding people with these diseases to actively screen for pancreatic cancer,it can play a posi-tive role in the prevention and treatment of pancreatic cancer in this area.