The relationship between paravertebral muscle changes with age and the degree of intervertebral disc degeneration
Objective To analyze the relationship between degenerative changes of paravertebral muscles with age and the degree of intervertebral disc degeneration.Methods The imaging data of 140 patients with lumbar disc herniation(LDH)were retrospectively analyzed.ImageJ software was used to measure the L4~S1 intervertebral disc and the cross-sectional areas of paravertebral muscles on MRI images of patients,and the cross-sectional area of functional relative paravertebral muscles was calculated.One-way analysis of variance was used to compare the differences in cross-sectional area of functional relative paravertebral muscles among different degrees of LDH at the same level and among different age groups.Spearman correlation analysis was employed to study the correlation between the degree of intervertebral disc degeneration,age and functional rel-ative paravertebral muscle cross-sectional area.Multifactor linear regression was used to study the factors in-fluencing functional relative paravertebral muscle cross-sectional area.Results At the L5/S1 and L4/L5 lev-els,there were statistically significant differences in functional relative paravertebral muscle cross-sectional area among different degrees of lumbar disc degeneration and different age groups.The degree of intervertebral disc degeneration and age were negatively correlated with the functional relative paravertebral muscle cross-sectional area at the same level(P<0.001).Age and degree of intervertebral disc degeneration were factors influencing functional relative paravertebral muscle cross-sectional area.Conclusion Paravertebral muscle degeneration is associated with age and intervertebral disc degeneration.
intervertebral disc degenerationagefunctional relative paravertebral muscle cross-sectional area