Objective To investigate the predictive value of homocysteine(Hcy)in the diagnosis of suba-cute combined degeneration of the spinal cord(SCD).Methods A retrospective analysis was conducted on 74 SCD patients hospitalized in the Department of Neurology at Liuzhou People's Hospital from November 2014 to June 2023,compared with 71 non-SCD patients hospitalized during the same period serving as the control group.Serum Hcy levels were collected from both groups.SPSS 26.0 software was used for statistical analy-sis.The receiver operating characteristic(ROC)curve was used to evaluate the predictive value of blood Hcy for SCD.Results The Hcy level in SCD patients[53.35(13.40～106.83)μmol/L]was significantly higher than that in the control group[13.20(10.00～14.90)μmol/L],with a statistically significant difference be-tween the two groups(P＜0.001).The ROC curve analysis showed that the area under the curve(AUC)for plasma Hey concentration in predicting SCD was 0.805(95％CI:0.728～0.882).Conclusion Hey levels in SCD patients are significantly higher than that of the control group,indicating potential application value in predicting the risk of SCD.
关键词
高同型半胱氨酸血症/脊髓亚急性联合变性/诊断
Key words
homocysteine/subacute combined degeneration of spinal cord/diagnosis
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