The predictive value of homocysteine in the diagnosis of subacute combined degeneration of spinal cord
Objective To investigate the predictive value of homocysteine(Hcy)in the diagnosis of suba-cute combined degeneration of the spinal cord(SCD).Methods A retrospective analysis was conducted on 74 SCD patients hospitalized in the Department of Neurology at Liuzhou People's Hospital from November 2014 to June 2023,compared with 71 non-SCD patients hospitalized during the same period serving as the control group.Serum Hcy levels were collected from both groups.SPSS 26.0 software was used for statistical analy-sis.The receiver operating characteristic(ROC)curve was used to evaluate the predictive value of blood Hcy for SCD.Results The Hcy level in SCD patients[53.35(13.40～106.83)μmol/L]was significantly higher than that in the control group[13.20(10.00～14.90)μmol/L],with a statistically significant difference be-tween the two groups(P＜0.001).The ROC curve analysis showed that the area under the curve(AUC)for plasma Hey concentration in predicting SCD was 0.805(95％CI:0.728～0.882).Conclusion Hey levels in SCD patients are significantly higher than that of the control group,indicating potential application value in predicting the risk of SCD.
homocysteinesubacute combined degeneration of spinal corddiagnosis
万方数据
维普
