摘要
目的 利用数据挖掘分析穴位按摩治疗负性情绪的选穴配伍规律,为负性情绪患者的穴位按摩提供参考依据.方法 以"穴位按摩""负性情绪""焦虑""抑郁"等为关键词,检索PubMed、Web of Science、中国知网、万方数据知识服务平台、中国生物医学文献数据库等数据库中相关的文献,建立穴位按摩治疗负性情绪的腧穴数据库,进行穴位频次描述性分析和配伍规律关联规则、复杂网络以及聚类分析.结果 最终纳入文献103篇,共含腧穴78个,针对人群多为神经科、心血管科的患者;最常用腧穴依次为百会、内关、合谷、太冲,多数腧穴分布在头项部及四肢,经络以督脉、足太阳膀胱经为主,特定穴以五输穴、原穴居多;关联规则表明,太冲、肝俞、合谷关联组合置信度最高,神经科负性情绪患者中百会、太冲、合谷配伍置信度最高,心血管科负性情绪患者,膻中、至阳配伍置信度最高;复杂网络显示核心处方为太冲、合谷、内关、太阳、百会;聚类分析得到腧穴聚类组合4组.结论 太冲、合谷、内关、太阳、百会是治疗负性情绪核心腧穴,穴位配伍治疗效果更好,数据挖掘所得结果对临床具有一定的参考价值.
Abstract
Objective To analyze the acupoint selection and compatibility rules in acupoint massage for the treatment of negative emotions using data mining,and to provide a reference for acupoint massage in patients with negative emotions.Methods Literature related to"acupoint massage""negative emotions""anxiety"and"depression"were searched in databases including PubMed,Web of Science,China National Knowledge Infra-structure(CNKI),Wanfang Data Knowledge Service Platform and China Biomedical Literature Database.An acupoint database for treating negative emotions was established.Descriptive analysis of acupoint frequency,association rules of compatibility rules,complex network and cluster analysis were conducted.Results A to-tal of 103 articles were included,comprising 78 acupoints.Most patients were from neurology and cardiovascu-lar departments.The most frequently used acupoints were Baihui,Neiguan,Hegu and Taichong.These acu-points were mainly distributed in the head,neck and limbs,with the Du Meridian and Foot Taiyang Bladder Meridian being predominant.Specific acupoints included Wushu Acupoints and Yuan-Source Acupoints.Asso-ciation rules showed that the combination of Taichong,Ganshu and Hegu had the highest confidence.In neu-rology patients with negative emotions,the compatibility of Baihui,Taichong and Hegu had the highest confi-dence,whereas in cardiovascular patients with negative emotions,the compatibility of Hanzhong and Zhiyang had the highest confidence.The complex network analysis revealed that the core prescriptions included Tai-chong,Hegu,Neiguan,Taiyang and Baihui.Four groups of acupoint combinations were obtained by cluster a-nalysis.Conclusion Taichong,Hegu,Neiguan,Taiyang and Baihui are the core acupoints for treating nega-tive emotions,and the therapeutic effect of acupoint compatibility is superior.The results derived from data mining provide valuable reference for clinical practice.
基金项目
安徽中医药大学自然科学研究重点项目(2021yfylc20)