首页|2015-2022年深圳市龙岗区HIV/AIDS新发现病例流行趋势特征和灰色模型定量预测

2015-2022年深圳市龙岗区HIV/AIDS新发现病例流行趋势特征和灰色模型定量预测

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目的 探讨HIV感染者/AIDS患者(HIV/AIDS)新发现病例流行特征和判定趋势、定量预测,为科学防控提供参考依据.方法 对深圳市龙岗区2015-2022年新发现HIV/AIDS病例用描述流行病学方法进行特征分析,用缓冲算子建立灰色均值GM(1,1)模型进行趋势判定和病例数预测.结果 2015-2022年龙岗区新发现HIV/AIDS病例共2722例(1 611/1 111),年均报告病例数(340±25)例.病例以男性(92.43%)、20~<40岁(71.49%)、未婚(63.67%)、高中及以上文化水平(68.59%)、商业服务和家务及待业(62.12%)、市外户籍(80.79%)病例为主,男男同性传播(68.41%)为主要感染途径.50岁以下以男男性传播为主,50岁以上以异性传播为主.医疗机构检测(56.61%)和咨询检测(25.24%)为主要发现方式.疫情趋势为:40~50岁(x2趋势=4.854,P<0.05)和>50岁(x2趋势=25.241,P<0.001)病例组分布呈增长趋势;家务及待业病例组分布呈增长趋势(x2趋势=6.533,P<0.05);医疗机构检测中其他就诊者检测分布呈增长趋势(x2趋势=20.558,P<0.001)和咨询检测分布呈下降趋势(x2趋势=10.562,P<0.05);新发现病例中AIDS构成比呈增长趋势(x2趋势=8.382,P<0.05);青、中、老年男性病例随着年龄的增加,有同性传播占比下降、异性传播占比上升趋势(x2趋势=252.478,P<0.001);男性未婚、离异或丧偶、已婚或有配偶组病例随着配偶的存在呈度同性传播占比下降、异性传播上升的趋势(x6势=155.454,P<0.001).弱化算子GM(1,1)灰色模型精度良好,显示近年疫情趋势平稳(发展系数<0.01),预测2023年病例数精度>95%,可用于HIV/AIDS新发现病例数预测.结论 龙岗区AIDS疫情态势平稳,但有中老年病例增加的趋势,病例发展到AIDS阶段因症状就诊发现的比例有增加趋势,应继续推行扩大检测策略及早发现病例,深入开展高危、重点人群综合干预防治措施,多渠道(尤其是在学校教育工作中)加强全民AIDS宣传教育和提高防护技能.灰色预测模型可有效判定AIDS疫情趋势和定量预测,对风险评估和疫情防控具有较好的指导意义.
Epidemic characteristics and grey model quantitative prediction of newly discovered HIV/AIDS cases in Longgang District,Shenzhen,2015-2022
Objective To explore the epidemic characteristics,determination trend and quantitative pre-diction of newly discovered cases of HIV/AIDS in order to provide reference for scientific prevention and con-trol.Methods A descriptive epidemiological method was used to analyze the characteristics of newly discov-ered AIDS cases in Longgang District,Shenzhen from 2015 to 2022,and a grey mean GM(1,1)model was es-tablished with buffer operators to determine the trend and predict the number of cases.Results From 2015 to 2022,a total of 2 722(1 611/1 111)new HIV/AIDS cases were identified in Longgang District,with an av-erage annual reported number of(340±25)cases.The majority of cases were male(92.43%),aged 20~<40 years(71.49%),unmarried(63.67%),with high school education or above(68.59%),engaged in commer-cial service,housework,or unemployed(62.12%),and household registration outside the city(80.79%).Male-to-male sexual transmission(68.41%)was the primary route of infection.Under the age of 50,male-to-male transmission predominated,while heterosexual transmission was more common above age 50.Medical in-stitution detection(56.61%)and counseling detection(25.24%)were the main detection methods.The epi-demic trends were as follows:there was an increasing trend in the distribution of cases for both 40 and 50 years old(xtrend=4.854,P<0.05)and>50 years old(x2trend=25.241,P<0.001);The distribution of housework and unemployment cases showed an increasing trend(xtrend=6.533,P<0.05).The detection distribution of other patients in medical institutions showed an increasing trend(x2trend=20.558,P<0.001)and the distribu-tion of counseling tests showed a decreasing trend(x2trend=10.562,P<0.05).The proportion of AIDS in new-ly discovered cases showed an increasing trend(xtrend=8.382,P<0.05).With the increase of age in males,the proportion of same-sex transmission decreased while heterosexual transmission increased(x2trend=252.478,P<0.001).In unmarried,divorced or widowed men,married or with spouses,the proportion of same-sex transmission decreased and the proportion of heterosexual transmission increased with the presence of spouses(Xtrend=155.454,P<0.001).The weakening operator GM(1,1)grey model demonstrated good accuracy,showing a stable epidemic trend in recent years(development coefficient<0.01).The model predicts 2023 case numbers with>95%accuracy,making it suitable for forecasting newly discovered HIV/AIDS cases.Conclusion While the AIDS epidemic situation in Longgang District remains stable,but there is an increasing trend of middle-aged and elderly cases and symptom-based diagnoses at the AIDS stage.It is necessary to con-tinue to implement the expanded detection strategy to detect cases early,and carry out comprehensive interven-tion and prevention measures for key groups.Multi-channel education,especially in the school,should be strengthened to improved the national AIDS awareness and protection skills.Grey prediction model can effec-tively determine AIDS epidemic trends and provides quantitative predictions,offering valuable guidance for risk assessment and epidemic prevention and control.

aequired immune deficiency syndromehuman immunodeficiency virusepidemic characteris-ticstendgrey prediction

孙春云、陈小燕、龙清平、叶伟雄

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广东省深圳市龙岗区疾病预防控制中心,广东 深圳 518172

获得性免疫缺陷综合征 人类免疫缺陷病毒 流行特征 趋势 灰色预测

深圳市龙岗区科技创新局科研项目

LGWJ2021-129

2024

右江民族医学院学报
右江民族医学院

右江民族医学院学报

影响因子:0.708
ISSN:1001-5817
年,卷(期):2024.46(4)