首页|泛免疫炎症指数对心肌梗死后射血分数下降的预测价值与决策树模型构建

泛免疫炎症指数对心肌梗死后射血分数下降的预测价值与决策树模型构建

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目的 构建决策树分类模型,以探讨急性心肌梗死(AMI)患者术后泛免炎症指数(PIV)变化对左心室射血分数(LVEF)下降的预测价值.方法 以2019年6月至2023年6月于皖南医学院第二附属医院确诊急性心肌梗死并行冠状动脉介入治疗的76名患者作为研究对象,收集术前、术后24 h内PIV变化水平.根据术后7~14 d内LVEF的变化,将人群分为LVEF下降组和非下降组,使用x2检验、T检验、U检验比较两组患者人口学资料及临床指标的组间差异,使用决策树分类模型探讨临床指标的分类价值及确定阈值.结果 LVEF值下降组24例与非下降组52例在术后PIV变化水平上差异有统计学意义(P<0.05).分类决策树发现,PIV值升高水平是否超过361.824是判断术后LVEF是否下降的根节点.术后中性粒细胞变化水平、术前EF值、胆红素水平、高密度脂蛋白是分类模型的重要子节点.结论 术后PIV升高与急性心肌梗死患者短期LVEF下降有关,具有临床参考价值.
Predictive value of Pan-immune inflammation value for reduced ejection fraction after myocardial infarction and the construction of decision tree model
Objective To investigate the correlation between changes in the preoperative and postoperative pan-immune inflammation value(PIV)and the changes in left ventricular ejection fraction(LVEF)at 7~14 days post-surgery in patients with acute myocardial infarction.Also,to construct a decision tree classification model to investigate the predictive value of PIV changes for reduced ejection fraction.Methods Seventy-six patients diagnosed with acute myocardial infarction and undergoing coronary artery intervention treatment at the second affiliated hospital of Wannan Medical College from 2019 to 2023 were included as the study subjects.Preoperative and postoperative PIV changes within 24 hours were collected,and the changes in LVEF between 7~14 days post-surgery were analyzed.Patients were divided into LVEF reduction group and non-reduction group.The Chi-square test,T-test,and U-test were used to compare the intergroup differences in demographic data and clinical indicators between the two groups.A decision tree classification model was used to explore the classification value of clinical indicators and determine the threshold.Results The LVEF reduction group(24 cases)and the non-reduction group(52 cases)showed significant differences in postoperative pan-immune in-flammation value(PIV)levels(P<0.05).The decision tree classification revealed that whether the increase in PIV value exceeded 361.824 was the root node for determining postoperative LVEF decline.Postoperative changes in neutrophil levels,preoperative EF value,bilirubin levels,and high-density lipoprotein were identi-fied as important subnodes in the classification model.Conclusion Postoperative elevation of PIV is associat-ed with short-term LVEF decline in patients with acute myocardial infarction,indicating clinical reference val-ue.

pan-immune inflammation valueacute myocardial infarctionmachine learningleft ventric-ular ejection fraction

干伟鹏、叶明全、宣靖、杨凌飞、张明超

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皖南医学院第二附属医院心血管内科,安徽 芜湖 241000

皖南医学院医学信息学院,安徽 芜湖 241000

皖南医学院研究生学院,安徽 芜湖 241000

泛免疫炎症指数 急性心肌梗死 机器学习 左室射血分数

教育部人文社会科学研究规划基金资助项目皖南医学院校中青年科研基金资助项目

22YJAZH134WK2023ZQNS24

2024

右江民族医学院学报
右江民族医学院

右江民族医学院学报

影响因子:0.708
ISSN:1001-5817
年,卷(期):2024.46(4)