The impact of controlling nutritional status scores on the evaluation and prognosis of patients with acute pancreatitis
Objective To explore the impact of controlling nutritional status(CONUT)score on the eval-uation and prognosis of acute pancreatitis(AP)patients.Methods 300 AP patients admitted were divided in-to non SAP group non-severe acute pancreatitis(non-SAP)and SAP groups,as well as survival and death groups.We compared clinical data at admission between these groups and evaluated factors influencing AP se-verity and prognosis,along with the predictive value of various indicators for AP condition.Results Except for gender,age,and TC,the SAP group showed significantly lower albumin(ALB)and lymphocyte(LYM)levels,but higher CONUT,Bedside Index for Severity in Acute Pancreatitis(BISAP),and Acute Physiology and Chronic Health Evaluation Ⅱ(APACHE Ⅱ)scores compared to the non-SAP group(P＜0.01).Except for gender and TC,the death group exhibited lower ALB and LYM levels,but higher CONUT,BISAP,and APACHE Ⅱ scores,as well as higher age,compared to the survival group(P＜0.01).Binary logistic regres-sion analysis showed that high BISAP and APACHE Ⅱ scores were risk factors for SAP occurrence(P＜0.05),while high ALB,LYM,and CONUT scores ≤2 were protective factors(P＜0.05).For 28-day mor-tality,advanced age and high BISAP and APACHE Ⅱ scores were risk factors(P＜0.05),whereas high ALB,LYM,and CONUT scores ≤2 were protective(P＜0.05).The combined indicators demonstrated high predictive value,with sensitivity and specificity of 89.3％and 79.4％for SAP occurrence,and 91.7％and 90.5％for 28-day mortality,respectively.Conclusion The CONUT score serves as risk factors of AP severi-ty and 28-day mortality.It proves to be an effective nutritional screening tool for AP patients.Moreover,the combination of CONUT with other indicators offers valuable predictive power for assessing AP severity and mortality risk,potentially improving patient management and outcomes.
pancreatitiscontrol nutritional status scoreprognosis
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