扫频OCTA观察不同眼轴近视患者视网膜—脉络膜血流及厚度的变化
SS-OCTA for observing retinal and choroidal blood flow and thickness changes in myopic patients with different axial lengths
陈亚茹 1徐梦月 1刘艳 1李娜 1许澈 1王剑锋1
作者信息
- 1. 蚌埠医科大学第一附属医院眼科,安徽 蚌埠 233000
- 折叠
摘要
目的 通过扫频光学相干断层扫描血管成像(SS-OCTA)技术分析不同眼轴长度(AL)近视眼黄斑区、视盘周围视网膜及脉络膜血流和厚度变化.方法 共纳入患者120例(212只眼),按照不同的AL分组;所有患者常规进行裂隙灯显微镜、眼压、眼底等检查,然后采用SS-OCTA扫描黄斑区和视盘区,定量分析扫描区域的视网膜、脉络膜血流密度及厚度.结果 随着AL的增加,黄斑区视网膜毛细血管血流密度减少;黄斑区浅层视网膜厚度(SRT)表现为减少而深层视网膜厚度(DRT)增加;脉络膜血管指数(CVI)、脉络膜血管体积比(CVV)、脉络膜基质体积比(CSV)均下降,脉络膜基质体积密度(CSI)增加;脉络膜厚度随眼轴增加而减少;视神经纤维层(RNFL)血流密度与厚度均逐渐减少,差异均有统计学意义(P＜0.05).视网膜中央凹无血管区(FAZ)、脉络膜毛细血管血流密度(CCP)、视神经乳头(ONH)参数各组间各象限两两相比差异均无统计学意义(P＞0.05).结论 SS-OCTA技术有助于定量评估近视患者视网膜脉络膜血流及厚度的改变,可用于近视患者常规眼底筛查及随访,便于早期发现近视患者眼底变化的趋势.
Abstract
Objective To analyze changes in macular blood flow and thickness,as well as peripapillary retinal and choroidal blood flow and thickness in myopic eyes with different axial lengths(AL)using swept-source optical coherence tomography angiography(SS-OCTA)technology.Methods A total of 120 patients(212 eyes)were enrolled and categorized according to different axial lengths.All patients underwent routine ophthalmic examination,including slit-lamp microscopy,ntraocular pressure,and fundoscopy,followed by SS-OCTA scanning of the macular and optic disc areas to quantitatively analyze retinal and choroidal blood flow density and thickness in the scanned regions.Results With the increase in AL,there was a decrease in the retinal capillary blood flow density in the macular area.The superficial retinal thickness(SRT)decreased while the deep retinal thickness(DRT)increased.The choroidal vascular index(CVI),choroidal vascular volume ra-tio(CVV),and choroidal stroma volume ratio(CSV)all decreased,and the choroidal stroma volume density(CSI)increased.Choroidal thickness decreased with the increase in eye axis.The blood flow density and thick-ness of the retinal nerve fiber layer(RNFL)gradually decreased and all differences were statistically significant(P＜0.05).The foveal avascular zone(FAZ),choriocapillaris blood flow density(CCP),and optic nerve head(ONH)parameters showed no statistically significant differences between groups for each quadrant(P 0.05).Conclusion SS-OCTA technology is helpful for the quantitative assessment of changes in retinal and choroidal blood flow and thickness in myopic patients,which can be used for routine fundus screening and fol-low-up in myopic patients,facilitating the early detection of trends in fundus changes in myopic patients.
关键词
近视/视网膜/脉络膜/扫频光学相干断层扫描血管成像/血流及厚度Key words
myopia/retinal/choroid/swept-source optical coherence tomography angiography/blood flow and thickness引用本文复制引用
基金项目
安徽高校自然科学研究重点项目(KJ2021A0718)
蚌埠医科大学研究生科研创新计划项目(Byycxz22065)
出版年
2024
NETL
NSTL
万方数据