SS-OCTA for observing retinal and choroidal blood flow and thickness changes in myopic patients with different axial lengths
Objective To analyze changes in macular blood flow and thickness,as well as peripapillary retinal and choroidal blood flow and thickness in myopic eyes with different axial lengths(AL)using swept-source optical coherence tomography angiography(SS-OCTA)technology.Methods A total of 120 patients(212 eyes)were enrolled and categorized according to different axial lengths.All patients underwent routine ophthalmic examination,including slit-lamp microscopy,ntraocular pressure,and fundoscopy,followed by SS-OCTA scanning of the macular and optic disc areas to quantitatively analyze retinal and choroidal blood flow density and thickness in the scanned regions.Results With the increase in AL,there was a decrease in the retinal capillary blood flow density in the macular area.The superficial retinal thickness(SRT)decreased while the deep retinal thickness(DRT)increased.The choroidal vascular index(CVI),choroidal vascular volume ra-tio(CVV),and choroidal stroma volume ratio(CSV)all decreased,and the choroidal stroma volume density(CSI)increased.Choroidal thickness decreased with the increase in eye axis.The blood flow density and thick-ness of the retinal nerve fiber layer(RNFL)gradually decreased and all differences were statistically significant(P＜0.05).The foveal avascular zone(FAZ),choriocapillaris blood flow density(CCP),and optic nerve head(ONH)parameters showed no statistically significant differences between groups for each quadrant(P 0.05).Conclusion SS-OCTA technology is helpful for the quantitative assessment of changes in retinal and choroidal blood flow and thickness in myopic patients,which can be used for routine fundus screening and fol-low-up in myopic patients,facilitating the early detection of trends in fundus changes in myopic patients.
myopiaretinalchoroidswept-source optical coherence tomography angiographyblood flow and thickness
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