Exploring the prescription patterns of Dendrobium in Xin'an Wang's internal medicine based on data mining
Objective To explore the prescription patterns of prescriptions of Dendrobium in Xin'an Wang's internal medicine.Methods The medical cases of the Xin'an Wang's internal medicine,represented by Wang Zhongqi,Wang Renzhi,and Wang Letao,were used as the primary sources for prescriptions.Pre-scriptions containing Dendrobium were selected and analyzed using the Xin'an Medical Data Information Appli-cation Platform software,the Apriori module in IBM SPSS Modeler 14.2,and SPSS 22.0 statistical software.Frequency statistics and association rule analysis were conducted to analyze the main indications,single medi-cine frequency,medicine combination frequency,and association rules in prescriptions containing Dendrobium.Results ①Prescriptions containing Dendrobium are commonly used for treating tuberculosis,hemoptysis,stroke,and cough.②High-frequency medicines include Poria Cocos,Tribulus Terrestris,Poria with host-wood,Glycine Soja、clam shell powder.③High-frequency medicine combinations include"Dendrobium with Poria cocos","Dendrobium with Tribulus Terrestris",and"Dendrobium with Poria with hostwood".④In the compatibility of Dendrobium with other medicines,single-single medicine prescriptions include Grossy Privet Fruit with Glycine Soja,and Madder with clam shell powder.Pair-single medicine prescriptions often include Glycine Soja and Poria with hostwood with Grossy Privet Fruit.Coltsfoot Flower,Coix Seed,clam shell pow-der,and Poria,commonly paired with Aster.⑤ For different indications treated with Dendrobium combina-tions,single medicines frequently combined with Dendrobium include Loquat Leaf,Stemona,and Rose for tu-berculosis,and Agrimony,Loofah Sponge,and Madder for hemoptysis.Medicines such as Aster,Coltsfoot Flower,Loquat Leaf,Coix Seed,and clam shell powder were commonly used for tuberculosis,while Loofah Sponge and Salvia were frequently used for hemoptysis.Conclusion The prescriptions containing Dendrobi-um in the Xin'an Wang's internal medicine are commonly used for conditions characterized by Yin deficiency and Yang hyperactivity.The medicine combinations reflects the idea of"combinations make medicines more ef-fective",with many compatible medicines having effects of nourishing yin and suppressing yang,tonifying the spleen and calming the mind,resolving phlegm and stopping cough,clearing heat and cooling the blood,and promoting blood circulation and dredging collateral.These combinations adhere to the principles of"treatment based on disease differentiation"and can achieve both root and symptom treatment,with clear and rigorous methods in formulating the prescriptions.
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