右江民族医学院学报2024,Vol.46Issue(6) :901-904,922.DOI:10.3969/j.issn.1001-5817.2024.06.012

广西地区196例男男性行为HIV感染者回顾性分析

Retrospective analysis of 196 HIV-infected men who have sex with men in Guangxi region

陆家荣 李铮 彭智鹏 唐秀生 黄思宇 郭婷 韦高 林有坤 彭俊文 郑文军
右江民族医学院学报2024,Vol.46Issue(6) :901-904,922.DOI:10.3969/j.issn.1001-5817.2024.06.012

广西地区196例男男性行为HIV感染者回顾性分析

Retrospective analysis of 196 HIV-infected men who have sex with men in Guangxi region

陆家荣 1李铮 2彭智鹏 3唐秀生 4黄思宇 1郭婷 1韦高 1林有坤 1彭俊文 1郑文军1
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作者信息

  • 1. 广西医科大学第一附属医院皮肤性病科,广西 南宁 530021
  • 2. 广西皮肤病医院麻风性病防治科,广西 南宁 530021
  • 3. 广西南宁市第四人民医院皮肤性病科,广西 南宁 530021
  • 4. 右江民族医学院附属医院皮肤性病科,广西 百色 533000
  • 折叠

摘要

目的 分析男男性行为HIV感染者临床流行病学特征及合并皮肤病、晚期肛门疾病(肛门高级别鳞状上皮内病变和/或肛门癌)状况.方法 从2003年1月至2023年12月广西医科大学第一附属医院、广西皮肤病医院、广西南宁市第四人民医院、右江民族医学院附属医院皮肤科住院的196例男男性行为HIV感染者中收集流行病学、合并皮肤病、晚期肛门疾病资料,分析相关的流行病学,皮肤病及晚期肛门疾病特征.结果 男男性行为HIV感染者年龄为(36.44±17.17)岁,多处于未婚(54.08%),文化程度多为高中(42.86%),职业以工人为主(31.63%).合并皮肤病的检出率为78.06%,合并单一皮肤病为42.35%,合并两种及以上皮肤病的检出率为35.71%,其中合并感染性皮肤病的检出率最高,为71.94%.男男性行为HIV感染者感染以金黄色葡萄球菌(42.35%)、念珠菌(56.12%)等为主.并且随着男男性行为HIV感染者CD4+T淋巴细胞计数水平减低,皮肤病的检出率及并发皮肤病种类增加.男男性行为HIV感染者晚期肛门疾病的检出率为21.94%,其与CD4+T淋巴细胞计数关联有统计学意义.结论 男男性行为HIV感染者以具备一定知识水平的未婚工人为主,需要对这一人群进行针对性地干预,以降低艾滋病感染率.男男性行为HIV感染者以合并皮肤病的种类繁多且检出率高,并发皮肤病的种类及其预后与患者自身免疫力密切相关.自身免疫力越低、并发皮肤病的种类越多,越容易并发晚期肛门疾病,预后越差.

Abstract

Objective To analyze the clinical epidemiological characteristics of men who have sex with men(MSM)with HIV infection,as well as the status of concurrent skin diseases and advanced anal diseases(high-grade squamous intraepithelial lesions of the anus and/or anal cancer).Methods Epidemiological data,data on concurrent skin diseases,and data on advanced anal diseases were collected from 196 HIV-infected MSM hospitalized in the department of dermatology of the First Affiliated Hospital of Guangxi Medical Univer-sity,Dermatology Hospital of Guangxi Zhuang Autonomous Region,the Fourth People's Hospital of Nan-ning,and the Affiliated Hospital of Youjiang Medical University for Nationalities between January 2003 and December 2023,and relevant epidemiology,skin diseases,and advanced anal disease characteristics were ana-lyzed.Results The mean age of the HIV-infected MSM was 36.44±17.17 years old,most of them were un-married(54.08%),with a high-school education level(42.86%),and the majority of their occupations were workers(31.63%).The detection rate of concurrent skin diseases was 78.06%,with 42.35%having a single skin disease and 35.71%having two or more skin diseases.The highest detection rate of concurrent skin disea-ses was infectious skin diseases(71.94%).Staphylococcus aureus(42.35%)and Candida(56.12%)were the main infections among MSM.As the CD4+T lymphocyte count decreased among HIV-infected MSM,the de-tection rate of skin diseases and the variety of concurrent skin diseases increased.The detection rate of ad-vanced anal diseases among HIV-infected MSM was 21.94%,and there was a statistically significant associa-tion with the CD4+T-lymphocyte count.Conclusion HIV-infected MSM are predominantly unmarried workers with a certain level of education,and targeted interventions are needed to reduce HIV infection rates a-mong this population.HIV-infected MSM have a high detection rate and variety of concurrent skin diseases,and the types and prognosis of concurrent skin diseases are closely related to patients'own immunity.The low-er the self-immunity,the more types of concurrent skin diseases,the more likely to develop advanced anal dis-eases,and the worse the prognosis.

关键词

男男性行为/HIV感染者/临床流行病学/皮肤病/晚期肛门疾病

Key words

men who have sex with men/HIV-infected individuals/clinical epidemiology/skin diseases/advanced anal diseases

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出版年

2024
右江民族医学院学报
右江民族医学院

右江民族医学院学报

影响因子:0.708
ISSN:1001-5817
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