Objective To investigate the causes and clinical characteristics of reoperation after phacoemulsification combined with intraocular lens implantation plus goniosynechialysis(PEI-GSL)for primary angle-closure glaucoma(PACG).Design Retrospective case series.Participants 1241 patients(1461 eyes)with PACG who underwent PEI-GSL in the Eye Hospital of Wenzhou from January 1,2018 to December 31,2021.Methods The patients'medical records were reviewed to analyze their clinical characteristics,type of re-operation,and reasons for reoperation.Main Outcome Measures Causes and clinical features of reoperation after PEI-GSL in patients with PACG.Results A total of 1241 PACG patients(1461 eyes)received PEI-GSL during the study period,including 17 patients(19 eyes)who received unplanned reoperation,with an incidence of 1.3％.Uncontrolled intraocular pressure was the main reason for reoper-ation,accounting for 73.7％.The complications such as residual lens cortex(5.3％),iris incarceration in corneal incision(5.3％),bag collapse(5.3％),deviation of intraocular lens(5.3％)and dilated pupil(5.3％)were the other reasons.The reason for uncontrolled in-traocular pressure after PEI-GSL include early angle closure(9 eyes,64.2％),late angle closure(3 eyes,21.4％)and trabecular mesh-work dysfunction(2 eyes,14.3％).All patients with early angle closure were women.Among them,6 eyes were CACG(66.7％),the me-dian outset of uncontrolled intraocular pressure after PEI-GSL was 16(1,46.5)days(range:1～60 days),the average range of anterior chamber angle synechiae before reoperation was(308.3±34.0)°(range:240°～360 °),the average central anterior chamber depth was(2.4±0.4)mm(range:1.7～3.1 mm),and 71.4％of patients had myopia drift.Conclusion The main reason for reoperation after PEI-GSL was uncontrolled intraocular pressure.Patients with early angle closure after PEI-GSL surgery may have anterior displacement of intraocular lens.(Ophthalmol CHN,2024,33:337-343)
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