Impact of Dexmedetomidine Dosage on Postoperative Pain and Recovery in Puerperae with Cesarean Section
Objective To explore the impact of dexmedetomidine dosage on postoperative pain and recovery in puerperae with cesarean section.Methods 150 primipara with cesarean section in our hospital from October 2021 to October 2022 were selected and randomly divided into group A(0.375%ropivacaine + saline),group B(0.375%ropivacaine + 0.5 μg/kg dexmedetomidine)and group C(0.375%ropivacaine + 1.0 μg/kg dexmedetomidine).The VAS score,colostrum time,prolactin level and adverse reactions were compared among the three groups.Results 6 h and 12 h after operation,the VAS scores of group B and C were lower than those of group A(P<0.05);No statistical difference was found in the VAS score between group B and group C(P>0.05).The colostrum time of group A was longer than that of group B and group C,and the prolactin level at 48 h after operation was lower than that of group B and group C(P<0.05);No statistical difference was found in the colostrum time and prolactin level at 48 h after operation between group B and group C(P>0.05).The incidence of nausea and vomiting in group A was higher than that in groups B and C(P<0.05);The incidence of bradycardia in group C was higher than that in groups A and B(P<0.05).Conclusions 0.5 μg/kg dexmedetomidine has best effect on postoperative analgesia in puerperae with cesarean section,which is conducive to postpartum recovery,with lower incidence of adverse reactions.