Observation on Effect of Linagliptin Combined with Semaglutide in the Treatment of Type 2 Diabetes Mellitus
Objective To observe the effect of linagliptin combined with semaglutide in the treatment of type 2 diabetes mellitus(T2DM).Methods 100 T2DM patients admitted to our hospital from March 2020 to February 2023 were divided into two groups.The control group was treated with linagliptin,and the observation group was treated with linagliptin combined with smectiglutide.The treatment effect,blood glucose level and adverse reactions were compared between the two groups.Results The total effective rate of treatment in the observation group was higher than that in the control group(P<0.05).After treatment,the FPG and 2hPG of the observation group were lower than those of the control group,and the FC-P and 2hC-P were higher than those of the control group(P<0.05).No statistical difference was found in the incidence of adverse reactions between the two groups(P>0.05).Conclusions Linagliptin combined with semaglutide has better effect in the treatment of T2DM,which can maintain the stability of blood glucose levels,and regulate the pancreatic islet function.