Observation on the Effect of Tirelizumab Combined with Apatinib in the Treatment of Advanced Gastric Cancer
Objective To analyze the clinical effect of tirelizumab combined with apatinib in the treatment of advanced gastric cancer.Methods A total of 78 patients with advanced gastric cancer were randomly divided into two groups.The control group was treated with apatinib,and the observation group was treated with tirelizumab combined with apatinib.The disease control,tumor marker levels and adverse reactions were compared between the two groups.Results The DCR of the observation group was 84.62%,higher than 61.54%of the control group(P<0.05).After treatment,the levels of CA125 and CEA in the two groups were lower than those before treatment(P<0.05),and the levels of CA125 and CEA in the observation group were lower than those in the control group(P<0.05).No significant difference was found in the total incidence of adverse reactions between the two groups(P>0.05).Conclusions Tirelizumab combined with apatinib in the treatment of advanced gastric cancer can significantly improve the disease control rate and reduce the levels of CA125 and CEA of patients,without significant increase of the occurrence of adverse reactions.
国家科技期刊平台
NSTL
万方数据
维普
