Impact of High-Dose Continuous Renal Replacement Therapy on Inflammatory Factor Levels and Microcirculation of Pa-tients with Emergency Sepsis
Objective To explore the application effect of high-dose continuous renal replacement therapy in the treatment of patients with emergency sepsis.Methods 62 patients with emergency sepsis were randomly divided into two groups.On the basis of conventional treatment,the control group was treated with conventional dose continuous renal replacement therapy,and the observation group was treated with high-dose continuous renal replacement therapy.The levels of inflammatory factors and the microcirculation indicators were compared between the two groups.Results After 48 hours of treatment,the levels of IL-6 and TNF-α in the two groups were lower than those before treatment,and the levels of IL-6 and TNF-α in the observation group were lower than those in the control group(P<0.05).After 48 hours of treatment,MFI and PPV in the two groups were higher than those before treatment,and MFI and PPV in the observation group were higher than those in the control group(P<0.05).Conclusions High-dose continuous renal replacement therapy in the treatment of patients with emergency sepsis can significantly reduce the levels of inflammatory factors and improve their microcirculation.
国家科技期刊平台
NSTL
万方数据
维普
