Observation on the Clinical Effect of Montelukast Sodium Combined with Loratadine in the Treatment of Allergic Rhinitis
Objective To explore the clinical effect of montelukast sodium combined with loratadine in the treatment of allergic rhinitis(AR).Methods 135 AR patients admitted to our hospital from January 2021 to December 2022 were selected and divided into two groups according to different treatment methods.The control group was treated with loratadine tablets,and the study group was treated with loratadine tablets combined with montelukast sodium tablets.The clinical efficacy,nasal physiological function and adverse reactions were compared between the two groups.Results The total effective rate of the study group was 97.06%,significantly higher than 86.57%of the control group(P<0.05).After treatment,the MTT of both groups was significantly shorter than that before treatment,and MCR and NR were significantly lower than those before treatment(P<0.05);The MTTs of the study group were significantly shorter than those of the control group,and MCR and NR were significantly lower than those of the control group(P<0.05).No significant difference was found in the total incidence of adverse reactions during treatment between the two groups(P>0.05).Conclusions Montelukast sodium combined with loratadine in the treatment of AR has exact effect,which can obviously improve patients'nasal function,and has high safety.
国家科技期刊平台
NSTL
万方数据
维普
